MCB 5270 Antimicrobial Resistance
Syllabus: Click Here
Cells are living factories that are capable of adapting their production line to any changes in the environment. Hence, cells encountering toxic environment will evolve their machinery to maintain survival and replication. Such adaptation, called Antimicrobial Resistance, is commonly observed across bacteria, viruses, parasites, and fungi. However, only recently the overuse of antimicrobial agents created a high selection pressure to drive a wide-spread of resistance. While we are currently witnessing a constant increase of antimicrobial resistance, the development of novel treatments has almost completely ceased. This course will provide an extensive background on antimicrobial resistance, treatments, and respective mechanisms.
After completion of this course, students should be able to:
– Outline problems associated with antimicrobial resistance across healthcare, agriculture, and the environment
– Explain resistance mechanisms in viruses, fungi, parasites, and cancer
– Identify major classes of antibiotics and their respective mechanisms of action
– Describe known mechanisms of antibiotic resistance and modes of transmission
– Identify means of detection/assessment of antibiotic resistance
– Describe therapeutic approaches used to fight antibiotic resistance
– Recognize scientific terms related to antimicrobial resistance
– Assess risks associated with antibiotic resistant infections
– Employ online databases to utilize genomic, chemical, and epidemiological data on AMR
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