MCB 6326 Computational Genomics and Epigenomics

Credits: 3

Tuition: $1,605

Syllabus: Click Here

Description

Genomics and epigenomics are emerging areas that utilize high-throughput sequencing technologies to allow rapid advances in our understanding of complicated biology questions. The primary goal of this course is to introduce students to the history, theory, latest advances, and computational approaches of genomics and epigenomics to prepare them for conducting large scale genomic analyses in their independent research. Course topics include but are not limited to sequence mapping and alignments, genome assembly, annotation and comparative genomics, variant identification and analysis (e.g. SNP calling and GWAS), transcriptomics (e.g. single-cell RNA-seq), small RNAs and long noncoding RNAs, DNA methylation, histone modification, open chromatin region (e.g. ATAC-seq), 3D chromatin interaction, cancer genomics, proteomics and phenomics.

Course Goals

After successful completion of this course, students should be able to gain:

• In-depth knowledge and understanding and mastery of the fundamental concepts and methodology of genomics and epigenomics.
• Familiarity with computational approaches and methods in analyzing different types of high-throughput genomic data.
• Understanding of the advantages and disadvantages of different computational approaches and methods.
• Demonstrated ability to interpret the data generated by the computational approaches and methods.

Library Access

Distance Education and UF Online Students enjoy the same library privileges as on-campus students.

• Utilize the University of Florida Library System