MCB 6937 Molecular Genetics
Syllabus: Click Here
This course will discuss the synthesis and manipulation of DNA and the principles of gene expression at the molecular level in both prokaryotes and eukaryotes. The topics covered will include an introduction to the concepts of DNA replication, repair and packaging of the genome into chromosomes. In preparation for this course, you should understand basic college-level introductory biology and it is recommended to have at least one other more specialized biology course, such as Microbiology, Botany, Zoology, Genetics or Biochemistry.
The goal of PCB4522 (Molecular Genetics) is for participants to understand the roles of DNA and RNA in both prokaryotes (eubacteria and Archaea) and eukaryotes, including yeast, plants, drosophila and man. Students will:
- Develop an appreciation of the organization and evolution of living systems and the role of genetic mutation and selection in the evolution of the human species.
- Acquire knowledge regarding DNA replication in bacteria, plasmids, transposable elements, as well as eukaryotic organelles and the nucleus.
- Become familiar with the molecular events involved in DNA repair and recombination.
- Acquire a detailed understanding of the molecular mechanisms related to gene expression at the transcriptional level, with an emphasis on eukaryotes.
- Learn to extract information from genomic databases and perform DNA sequence analyses using online bioinformatics tools.
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